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Philosophy of Science — Key Points

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1. Central questions - What distinguishes science from non-science? (Demarcation problem) - How do scientific theories explain and predict phenomena? - What is the nature of scientific reasoning (induction, deduction, abduction)? - How do observation and theory interact (theory-ladenness of observation)? - What is the status of scientific knowledge (realism vs. anti-realism)? 2. Major positions - Scientific Realism: Best scientific theories approximately truthfully describe unobservable entities (Putnam, Boyd). - Instrumentalism/Anti-Realism: Theories are tools for prediction, not necessarily true descriptions (van Fraassen). - Constructivism and Social Epistemology: Scientific knowledge is shaped by social processes, values, and institutions (Kuhn, Latour). - Structuralism and Model-Based Views: Science advances via models and structures rather than literal true statements (Suppe, Cartwright). 3. Methodology and reasoning - Induction: Generalizing from observations—problem of justifying induction (Hume). - Falsificationism: Popper’s idea that theories are scientific if falsifiable; emphasizes bold conjectures and refutations. - Bayesianism: Probabilistic updating of belief based on evidence. - Lakatos’ Research Programmes: Science progresses through competing research programmes with heuristics and protective belts. 4. Explanation and laws - Covering-law model: Explanations subsume phenomena under general laws (Hempel). - Causal/mechanistic accounts: Explanations cite causes or mechanisms producing phenomena (Salmon, Craver). - Pragmatic and pluralist views: Multiple types of explanation depending on context. 5. Values, objectivity, and ethics - Science aims for objectivity, but choices about methods, significance, and application involve epistemic and non-epistemic values. - Responsible research requires transparency, reproducibility, and ethical reflection. 6. Contemporary issues - Replication crisis and reliability of findings. - Role of models, simulations, and big data. - Science policy, public trust, and science communication. Further reading (concise) - Peter Godfrey-Smith, Theory and Reality (2003) - Karl Popper, The Logic of Scientific Discovery (1959) - Thomas Kuhn, The Structure of Scientific Revolutions (1962) - Bas van Fraassen, The Scientific Image (1980) If you want, I can explain any one of these points in more detail or compare specific positions (e.g., realism vs. van Fraassen).

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Replication Crisis and Reliability of Findings

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The replication crisis refers to the widespread discovery that many published scientific results—especially in psychology, biomedical sciences, and some social sciences—fail to be reproduced when independent researchers repeat the same studies. Replication is a basic scientific test: if a finding reflects a real effect, other competent investigators using the same methods should obtain similar results. When replications fail, confidence in the original claim, its methods, or underlying theory is undermined. Key causes - Low statistical power: small sample sizes make false positives and effect-size exaggeration more likely. - P-hacking and selective reporting: researchers (consciously or not) try many analyses and report only those that reach conventional significance (p < .05). - Publication bias: journals favor novel, positive results over null or replication studies, skewing the literature. - Poor methodological transparency: insufficient reporting of materials, data, and procedures prevents exact replication. - Questionable research practices and incentives: career pressures prioritize quantity and novelty over rigor. Consequences for reliability - Many published effects are overestimated or false, reducing trust in disciplines and slowing cumulative knowledge. - Meta-analyses and policy decisions built on biased literature may mislead practice. - Replication failures prompt re-evaluation of methods, theories, and standards of evidence. Responses and reforms - Pre-registration of study plans and hypotheses to limit fishing for significance (Nosek et al., 2018). - Open data, materials, and code to enable exact replication and reanalysis (Munafò et al., 2017). - Larger, better-powered studies and multi-lab replications (Simons et al., 2014). - Registered reports and journal reforms that commit to publishing based on methods rather than results. - Improved statistical practices: emphasis on effect sizes, confidence intervals, Bayesian methods, and better correction for multiple testing. Implication for philosophy of science The crisis highlights tensions between idealized models of scientific progress (cumulative, self-correcting) and the practice shaped by human, social, and institutional factors. It stresses the importance of methodological norms, transparency, and incentives for reliable knowledge production (Ioannidis, 2005). Suggested readings - Ioannidis, J. P. A. (2005). “Why Most Published Research Findings Are False.” PLoS Medicine. - Nosek, B. A., et al. (2018). “The preregistration revolution.” Proceedings of the National Academy of Sciences. - Open Science Collaboration (2015). “Estimating the reproducibility of psychological science.” Science.

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